A 10-year-old CNN outperforms frontier LLMs for skin cancer diagnosis
A dermatologist tested GPT-6 Astra and Claude Fable 5.1 on 200 biopsy-proven lesions from MILK10k, giving each a clinical and a dermoscopic image. A CNN (Inception v3, fine-tuned for about twenty minutes on 68,011 ISIC images) named the right diagnosis for 62% of lesions, against 42% for both LLMs. The post lists caveats (small sample, single run, possible contamination) and links the cases, prompts, replies and scoring code.
evals, multimodalΒ· Added 26 Oct 2026, published 25 Oct 2026





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